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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
27.27
Human Site:
S149
Identified Species:
46.15
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S149
Q
L
K
Q
D
I
L
S
G
K
L
D
C
P
F
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S149
Q
L
K
Q
D
I
L
S
G
K
L
D
C
P
F
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
S149
Q
L
K
Q
D
I
L
S
G
K
L
D
C
P
F
Dog
Lupus familis
XP_532028
914
101864
S231
Q
L
R
H
D
I
L
S
G
K
L
K
C
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S149
Q
L
K
Q
D
I
L
S
G
K
L
E
C
P
F
Rat
Rattus norvegicus
Q5FVG2
731
81700
S149
Q
L
K
Q
D
I
L
S
G
K
L
E
C
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
G162
A
K
W
L
E
M
Y
G
V
D
M
H
V
V
K
Chicken
Gallus gallus
XP_422083
502
57358
Frog
Xenopus laevis
NP_001080234
498
57093
Zebra Danio
Brachydanio rerio
O57457
619
70690
R60
E
T
E
Y
F
G
V
R
Y
C
D
R
S
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
E164
Q
L
K
Q
D
L
L
E
G
R
L
D
C
P
E
Honey Bee
Apis mellifera
XP_623974
809
90976
E228
Q
L
K
Q
D
V
L
E
G
K
L
H
C
P
H
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
S283
V
A
N
E
D
G
V
S
E
T
I
M
I
F
N
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
T144
Q
L
K
E
D
I
R
T
G
R
L
E
V
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
100
73.3
N.A.
93.3
93.3
N.A.
0
0
0
0
N.A.
73.3
73.3
13.3
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
20
0
0
20
N.A.
86.6
80
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
58
0
0
% C
% Asp:
0
0
0
0
72
0
0
0
0
8
8
29
0
0
0
% D
% Glu:
8
0
8
15
8
0
0
15
8
0
0
22
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
36
% F
% Gly:
0
0
0
0
0
15
0
8
65
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
15
0
8
8
% H
% Ile:
0
0
0
0
0
50
0
0
0
0
8
0
8
0
0
% I
% Lys:
0
8
58
0
0
0
0
0
0
50
0
8
0
0
8
% K
% Leu:
0
65
0
8
0
8
58
0
0
0
65
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% P
% Gln:
65
0
0
50
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
8
0
0
0
8
8
0
15
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
0
0
0
8
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
15
0
8
0
0
0
15
8
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _